文章摘要
张曙云,俞小忠,陈渠通,夏燕,董敏.2666例体检人群不同肥胖类型与胰岛素抵抗的相关性分析[J].,2017,39(15):1287-1290.
2666例体检人群不同肥胖类型与胰岛素抵抗的相关性分析
Association between central obesity and insulin resistance
  
DOI:10.12056/j.issn.1006-2785.2017.39.15.2016-961
中文关键词: 肥胖 胰岛素抵抗 腰围 体重指数
英文关键词: Obesity Insulin resistance Waist circumference Body mass index
基金项目:
作者单位
张曙云 南京军区杭州疗养院检验科 
俞小忠  
陈渠通  
夏燕  
董敏  
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中文摘要:
      目的探讨不同肥胖类型与胰岛素抵抗(IR)之间的关系。方法测量2666例体检者的身高、体重、腰围、臀围、空腹血糖和空腹胰岛素等指标。结果男性组肥胖率和中心性肥胖率分别为13.61%和55.26%、女性组分别为3.46%和24.76%,男性组高于女性组(P<0.05)。胰岛素抵抗指数(HOMA-IR)和胰岛β细胞功能指数(HOMA-β)随着BMI增加而增加,同时中心性肥胖者的HOMA-IR和HOMA-β明显高于腰围正常组(均P<0.05)。通过多重逐步回归分析HOMA-IR的影响因素为BMI、腰围和年龄;男性组中HOMA-β的影响因素为体重、年龄、身高和BMI;女性中的影响因素是年龄、BMI和腰臀比。结论IR与肥胖类型和年龄等有关,因此随着年龄的增加更加需要控制体重,尤其要预防中心性肥胖的发生,才能降低糖尿病的风险。
英文摘要:
      Objective To analyze the relationship between central obesity and insulin resistance. Methods Total 2666 subjects underwent health check-up in Hangzhou sanatorium during 2015, the height, weight, waist and hip circumference, blood glucose and insulin levels were measured. Results The prevalence of obesity in males and females was 13.61% and 3.46% , respectively (P <0.05). The rates of central obesity were 55.26% and 24.76% in male and female obese subjects, respectively (P<0.05). HOMA-IR and HOMA- β increased with the increase of BMI, while HOMA-IR and HOMA- β in central obesity were significantly higher than those in non-central obesity group (P<0.05). Multiple stepwise regression analysis that the factors related to HOMA-IR were BMI, waist circumference and age, the factors related to HOMA- β were weight, age, height and BMI in males, while age, BMI and waist to hip ratio in females. Conclusion Insulin resistance is likely to develop in subjects with central obesity, it is necessary to prevent the occurrence of central obesity for reducing the risk of diabetes.
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